Bi23: Random Processes in Biology
Instructor: Dr. Joshua Milstein
Office: 200T BBB
Email: milstein@caltech.edu
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Bi23: Random Processes in Biology Instructor: Dr. Joshua Milstein Office: 200T BBB Email: milstein@caltech.edu | |
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Summary: This class will focus on selected topics
throughout biology where probability and randomness play a significant
role. We'll see that determinism is not the norm in most
biological systems, that significant levels of noise are often
present, and that sometimes this noise may be put to good use to help
an organism adapt and survive. Download Syllabus |
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Single-Photon Detection of Cells J.L. Schnapf and D.A. Baylor, How photoreceptor cells respond to light. Sci. Am., 256(4), 40 (1987). F. Rieke and D.A. Baylore, Single-photon detection by rod cells of the retina. Rev. of Mod. Phys., 70, 1027 (1998). Bacterial Motion E. M. Purcell, Life at low Reynolds number. Am. J. Phys., 45, 3 (1977). H.C. Berg, Bacterial Motility and Behavior. Phys. Tod., 53, 24 (2000). H.C. Berg, Marvels of Bacterial Behavior. Proc. Am. Phil. Soc., 150, 428 (2006). Molecular Motors R. D. Astumian and P. Hanggi, Brownian motors. Phys. Tod., 55, 33 (2002). Noise Enhancement and Perception P. Hanggi, Stochastic Resonances in Biology, Chemphyschem., 3, 285 (2002). Neurons and the Brain A. A. Faisal, J.A. White and S. B. Laughlin, Ion-Channel Noise Places Limits on the Miniaturization of the Brain's Wiring, Curr. Bio., 15, 1143 (2005). J.A. White, J.T. Rubinstein and A. R. Kay, Channel noise in neurons, TINS, 23, 131 (2000). Genetic Regulation B.B. Kaufman and A. van Oudenaarden, Stochastic Gene Expression: From Single Molecules to the Proteome. Curr. Opin. Genet. Dev., 17, 107 (2007). N. Fedoroff and W. Fontana, M. Elowitz, |